THE ARTHRITIS SEVERITY LOCUS CIA5A REGULATES THE EXPRESSION OF INFLAMMATORY MEDIATORS INCLUDING SYK PATHWAY GENES AND PROTEASES IN PRISTANE-INDUCED ARTHRITIS

The arthritis severity locus Cia5a regulates the expression of inflammatory mediators including Syk pathway genes and proteases in pristane-induced arthritis

Abstract Background Cia5a is a locus on rat chromosome 10 that regulates disease severity and joint damage in two models of rheumatoid arthritis, collagen- and pristane-induced arthritis (PIA).In this study, we aimed to identify cellular and molecular processes regulated by Cia5a using microarray-based gene expression analysis of synovial tissues f

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Left ventricular hypertrophy, geometric patterns and clinical correlates among treated hypertensive Nigerians

BACKGROUND: Left ventricular hypertrophy can be due to various reasons including hypertension.It constitutes an increased cardiovascular risk.Various left ventricular geometric patterns occur in hypertension and may affect the cardiovascular risk profile of hypertensive subjects.METHODS: One hundred and eighty eight cereal box hypertensive subjects

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